Clinical pharmacokinetics and pharmacodynamics : concepts and applications /

Title:

Clinical pharmacokinetics and pharmacodynamics : concepts and applications /

Author:

Rowland, Malcolm.

Format:

Book

Institution:

MCPHS Boston, MCPHS Worcester

Contents:

Therapeutic relevance -- Fundamental concepts and terminology -- Kinetics following an intravenous bolus dose -- Membranes and distribution -- Elimination -- Kinetics following an extravascular dose -- Absorption -- Response following a single dose -- Therapeutic window -- Constant-rate input -- Multiple-dose regimens -- Variability -- Genetics -- Age, weight, and gender -- Disease -- Nonlinearities -- Drug interactions -- Initiating and managing therapy -- Distribution kinetics -- Metabolites and drug response -- Protein drugs -- Prediction and refinement of human kinetics from in vitro, preclinical, and early clinical data.

Online access:

No online access

Library holdings:

MCPHS Circulation - Boston Campus
RM301.5 .R68 2011 – Available

MCPHS Circulation - Manchester Campus
RM301.5 .R68 2011 – Available

• Available Temporarily at MCPHS Manchester Reserve
  On reserve for Manchester Reserve List ((All departments): (none))

MCPHS Circulation - Worcester Campus
RM301.5 .R68 2011 – Available